Thunderbird could not sending and receiving emails although it kept trying, after my old profile folder was moved to a new location. Error console showed the following message.
Your certificate contains the same serial number as another certificate issued by the certificate authority. Please get a new certificate containing a unique serial number. (Error code: sec_error_reused_issuer_and_serial)
For more information, see https://support.mozilla.org/en-US/kb/Certificate%20contains%20the%20same%20serial%20number%20as%20another%20certificate.